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Article

Changes in lamina structure are followed by spatial reorganization of heterochromatic regions in caspase-8-activated human mesenchymal stem cells.

Journal of cell science - 15 Oct 2006

Raz Vered, Carlotti Françoise, Vermolen Bart J, van der Poel Egge, Sloos Willem C R, Knaän-Shanzer Shoshan, de Vries Antoine A F, Hoeben Rob C, Young Ian T, Tanke Hans J, Garini Yuval, Dirks Roeland W

Abstract excerpt

Apoptosis is fundamental to the regulation of homeostasis of stem cells in vivo. Whereas the pathways underlying the molecular and biochemical details of nuclear breakdown that accompanies apoptosis have been elucidated, the precise nature of nuclear reorganization that precedes the demolition phase is not fully understood. Here, we expressed an inducible caspase-8 in human mesenchymal stem cells, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17003109
DOI: 10.1242/jcs.03180

Genes

PML

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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