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Article

Objective assessment of changes in nuclear morphology and cell distribution following induction of apoptosis

12 May 2014

Abstract excerpt

BACKGROUND: To objectively measure changes in nuclear morphology and cell distribution following induction of apoptosis. METHODS: A spontaneously immortalized retinal pigment epithelial cell line (ARPE-19) was cultured for three days in DMEM/F12 with 10% fetal bovine serum followed by 24 hours incubation in staurosporine to induce apoptosis. Cells that were not incubated in staurosporine served as control....

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PMID: 24885713
DOI: 10.1186/1746-1596-9-92

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