Article
Coordination of meiotic recombination, pairing, and synapsis by PHS1.
Science (New York, N.Y.) - 2 Jan 2004
Pawlowski Wojciech P, Golubovskaya Inna N, Timofejeva Ljudmilla, Meeley Robert B, Sheridan William F, Cande W Zacheus
Abstract excerpt
Pairing, synapsis, and recombination are prerequisites for accurate chromosome segregation in meiosis. The phs1 gene in maize is required for pairing to occur between homologous chromosomes. In the phs1 mutant, homologous chromosome synapsis is completely replaced by synapsis between nonhomologous partners. The phs1 gene is also required for installation of the meiotic recombination machinery on chromosomes, as...
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