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Article

Structural organization of the murine c-kit proto-oncogene.

Oncogene - 1 Jul 1992

Gokkel E, Grossman Z, Ramot B, Yarden Y, Rechavi G, Givol D

Abstract excerpt

The murine Kit receptor gene on chromosome 5 has been found to be frequently involved in germline mutations and rearrangements, leading to a characteristic set of severe developmental defects, known as the W phenotype. Here we describe the structure of the murine c-kit gene, based on restriction analysis of genomic phage clones and sequence determination of exon-intron boundaries. The Kit-coding region is...

Topics

Amino Acid Sequence
Animals
Base Sequence
Exons
Genomic Library
Humans
Introns
Mice
Molecular Sequence Data
Mutation
Proto-Oncogene Mas
Proto-Oncogene Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Proto-Oncogene Proteins c-kit

Receptor, Macrophage Colony-Stimulating Factor

Sequence Homology, Nucleic Acid

Source

Identifiers

PMID: 1377813

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1377813-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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