Article
Mutagenic effect of cadmium on tetranucleotide repeats in human cells.
Mutation research - 1 Dec 2006
Slebos Robbert J C, Li Ming, Evjen Amy N, Coffa Jordy, Shyr Yu, Yarbrough Wendell G
Abstract excerpt
Cadmium is a human carcinogen that affects cell proliferation, apoptosis and DNA repair processes that are all important to carcinogenesis. We previously demonstrated that cadmium inhibits DNA mismatch repair (MMR) in yeast cells and in human cell-free extracts (H.W. Jin, A.B. Clark, R.J.C. Slebos, H. Al-Refai, J.A. Taylor, T.A. Kunkel, M.A. Resnick, D.A. Gordenin, Cadmium is a mutagen that acts by inhibiting...
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