Article
Is cadmium genotoxic?
IARC scientific publications - 1 Jan 1992
Rossman T G, Roy N K, Lin W C
Abstract excerpt
Previous evidence that cadmium(II) causes gene mutations in bacteria or mammalian cells was weak. However, alterations in protocol have recently led to better evidence for its mutagenicity, especially in bacteria. Mutagenicity results may be confounded by tolerance mechanisms. Exposure of DNA in vitro to Cd2+ or to Cd2+ hydrogen peroxide does not result in strand breaks or alkali-labile sites. The fact that...
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