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Article

Acceleration of cortical thinning in familial Alzheimer's disease.

Neurobiology of aging - 1 Oct 2011

Knight W D, Kim L G, Douiri A, Frost C, Rossor M N, Fox N C

Abstract excerpt

BACKGROUND: MRI in presymptomatic autosomal dominant Alzheimer's disease mutation carriers (MC) provides an opportunity to detect changes that pre-date symptoms or clinical diagnosis. We used automated cortical thickness (CTh) measurement to compare the grey matter of such a group with cognitivel...

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Source

Identifiers

PMID: 20005601
DOI: 10.1016/j.neurobiolaging.2009.11.013

Genes

APP
PSEN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20005601-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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