Article
Disruption of parental-specific expression of imprinted genes in uniparental fetuses.
FEBS letters - 2 Oct 2006
Ogawa Hidehiko, Wu Qiong, Komiyama Junichi, Obata Yayoi, Kono Tomohiro
Abstract excerpt
In mammals, imprinted genes show parental origin-dependent expression based on epigenetic modifications called genomic imprinting (GI), which are established independently during spermatogenesis or oogenesis. Due to GI, uniparental fetuses never develop to term. To determine whether such expression of imprinted genes is maintained in uniparental mouse fetuses, we analyzed the expression of 20 paternally and 11...
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