Article
The non-viability of uniparental mouse conceptuses correlates with the loss of the products of imprinted genes.
Mechanisms of development - 1 Apr 1994
Walsh C, Glaser A, Fundele R, Ferguson-Smith A, Barton S, Surani M A, Ohlsson R
Abstract excerpt
Diploid parthenogenetic or androgenetic mouse conceptuses produce characteristic and opposite mutant phenotypes and are non-viable, presumably due to different contributions from the maternal and paternal genomes. This is likely to be the result of the preferential expression of only one parent's...
Topics
- Animals
- DNA
- Embryo, Mammalian
- Embryonic and Fetal Development
- Female
- Gene Expression
- Genes
- Genome
- In Situ Hybridization
- Mice
- Mice, Inbred C57BL
- Mice, Inbred CBA
