Article
Identification and resolution of artifacts in the interpretation of imprinted gene expression.
Briefings in functional genomics - 1 Dec 2010
Proudhon Charlotte, Bourc'his Déborah
Abstract excerpt
Genomic imprinting refers to genes that are epigenetically programmed in the germline to express exclusively or preferentially one allele in a parent-of-origin manner. Expression-based genome-wide screening for the identification of imprinted genes has failed to uncover a significant number of new imprinted genes, probably because of the high tissue- and developmental-stage specificity of imprinted gene...
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