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Article

Unregulated expression of the imprinted genes H19 and Igf2r in mouse uniparental fetuses.

The Journal of biological chemistry - 5 Apr 2002

Sotomaru Yusuke, Katsuzawa Yukiko, Hatada Izuho, Obata Yayoi, Sasaki Hiroyuki, Kono Tomohiro

Abstract excerpt

The present study shows that the H19 and Igf2r genes, which are imprinted and expressed solely from maternal alleles, are expressed in an unregulatable manner in mouse uniparental, androgenetic, and parthenogenetic fetuses at day 9.5 of gestation. In the androgenetic fetuses, the H19 and Igf2r genes were respectively expressed at 12 and 40% of the levels in biparental fetuses. In addition, the expression of both...

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Identifiers

PMID: 11805093
DOI: 10.1074/jbc.M109212200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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