Article
Physiological functions of imprinted genes.
Journal of cellular physiology - 1 Sept 2002
Tycko Benjamin, Morison Ian M
Abstract excerpt
Genomic imprinting in gametogenesis marks a subset of mammalian genes for parent-of-origin-dependent monoallelic expression in the offspring. Embryological and classical genetic experiments in mice that uncovered the existence of genomic imprinting nearly two decades ago produced abnormalities of growth or behavior, without severe developmental malformations. Since then, the identification and manipulation of...
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