Quantitative analysis of CD5 antigen modulation by 12-O-tetradecanoylphorbol-13-acetate in T-lymphoblastic leukemia cells: individual response patterns and their relationships with both maturation and protein kinase C content.

doi:10.1016/0008-8749(90)90277-x

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Article

Quantitative analysis of CD5 antigen modulation by 12-O-tetradecanoylphorbol-13-acetate in T-lymphoblastic leukemia cells: individual response patterns and their relationships with both maturation and protein kinase C content.

Cellular immunology - 15 Oct 1990

Chiron M, Darbon J M, Roubinet F, Cassar G, Jaffrezou J P, Bordier C, Laurent G

Abstract excerpt

Modulation of CD5 expression by TPA was investigated on T-leukemic cell lines corresponding to different stages of ontogeny. These CD5 changes have been analyzed simultaneously with modifications of cell growth, cell cycle, cell surface phenotype, and PKC content. CD5 expression was found 6- to 1...

Topics

1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine
Antigens, Differentiation
Antigens, Differentiation, T-Lymphocyte
CD5 Antigens
Cell Cycle
Cell Differentiation
Cell Division
Diglycerides
Flow Cytometry
Gene Expression Regulation, Neoplastic
Humans
Isoquinolines
Leukemia, T-Cell

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Phenotype

Piperazines

Protein Kinase C

Tetradecanoylphorbol Acetate

Tumor Cells, Cultured

Source

Open in PubMed

Identifiers

PMID: 1698561
DOI: 10.1016/0008-8749(90)90277-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-1698561-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.