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Article

Differentiation of acute and chronic myeloid leukemic blasts into the dendritic cell lineage: analysis of various differentiation-inducing signals.

Cancer immunology, immunotherapy : CII - 1 Jan 2005

Kharfan-Dabaja Mohamed, Ayala Ernesto, Lindner Inna, Cejas Pedro J, Bahlis Nizar J, Kolonias Despina, Carlson Louise M, Lee Kelvin P

Abstract excerpt

PURPOSE: Ex vivo differentiation of myeloid leukemic blasts into dendritic cells (DCs) holds significant promise for use as cellular vaccines, as they may present a constellation of endogenously expressed known and unknown leukemia antigens to the immune system. Although variety of stimuli can drive leukemia --> DC differentiation in vitro, these blast-derived DCs typically have aberrant characteristics compared...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 15693136
DOI: 10.1007/s00262-004-0562-4
PMCID: PMC11032788

Genes

TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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