Article
In vitro differentiation of a Hodgkin's disease derived cell line.
Hematological oncology - 1 Jan 2000
Klein S, Jones D B, Tesch H
Abstract excerpt
We have examined the Hodgkin's disease derived cell line Co in terms of its capacity to differentiate in vitro. Co cells show the characteristics of immature T cells and express CD3 molecules in the cytoplasm. On activation with 12-O-tetradecanoylphorbol-13-acetate (TPA) these cells express the C...
Topics
- CD3 Complex
- CD4 Antigens
- CD8 Antigens
- Cell Transformation, Neoplastic
- Enzyme-Linked Immunosorbent Assay
- Fluorescent Antibody Technique
- Gene Expression Regulation, Neoplastic
- Hodgkin Disease
- Humans
- Interleukin-2
- Interleukin-3
- Interleukin-4
- Interleukin-8
- Phenotype
- Receptors, Antigen, T-Cell, alpha-beta
- Receptors, Interleukin-2
- T-Lymphocytes
- Tetradecanoylphorbol Acetate