Article
Functional and phenotypic upregulation of CD13/aminopeptidase-N on precursor-B acute lymphoblastic leukemia after in vitro stimulation.
Experimental hematology - 1 Oct 1995
Makrynikola V, Favaloro E J, Browning T, Bianchi A, Bradstock K F
Abstract excerpt
Acute lymphoblastic leukemia (ALL) cells of precursor-B type were assessed for expression of the cell surface peptidase CD13 (aminopeptidase-N) after 72 hours' culture in 10% B cell growth factor (BCGF), TPA, or medium alone. CD13 was analyzed phenotypically using a specific monoclonal antibody (...
Topics
- Adolescent
- Adult
- Aged
- Antibodies, Monoclonal
- Antigens, CD
- B-Lymphocytes
- Blast Crisis
- Bone Marrow
- CD13 Antigens
- Cells, Cultured
- Child, Preschool
- Female
- Flow Cytometry
- Fluorescent Antibody Technique
- Gene Expression
- Hematopoietic Stem Cells
- Humans
- Interleukin-4