Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription.

BMC molecular biology - 19 Sept 2006

James Claudine G, Woods Anita, Underhill T Michael, Beier Frank

Abstract excerpt

BACKGROUND: Coordinated chondrocyte proliferation and differentiation are required for normal endochondral bone growth. Transcription factors binding to the cyclicAMP response element (CRE) are known to regulate these processes. One member of this family, Activating Transcription Factor 3 (ATF3),...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chondrocytes
Share to Core Binding Factor Alpha 1 Subunit
Share to Cyclic AMP Response Element-Binding Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin A

Share to Cyclin D1

Share to Cytochalasin D

Share to High Mobility Group Proteins

Share to SOX9 Transcription Factor

Source

Open in PubMed Open full text

Identifiers

PMID: 16984628
DOI: 10.1186/1471-2199-7-30
PMCID: PMC1584246

Genes

ATF3
RUNX2
SOX9

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-16984628-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The transcription factor ATF3 is upregulated during chondrocyte differentiation and represses cyclin D1 and A gene transcription.PMID 16984628Read ↗

Activating transcription factor 2 is necessary for maximal activity and serum induction of the cyclin A promoter in chondrocytes.Semantic proximity Read ↗

ATF3 deficiency in chondrocytes alleviates osteoarthritis developmentSemantic proximity Read ↗

A network of transcriptional and signaling events is activated by FGF to induce chondrocyte growth arrest and differentiationSemantic proximity Read ↗

Runx3/AML2/Cbfa3 Regulates Early and Late Chondrocyte DifferentiationSemantic proximity Read ↗

Regulation of Cartilage Development and Diseases by Transcription FactorsSemantic proximity Read ↗

Activating transcription factor-2 affects skeletal growth by modulating pRb gene expression.Semantic proximity Read ↗

Regulation of the transcriptional activation of CTRP3 in chondrocytes by c-Jun.Semantic proximity Read ↗

Constitutive E2F1 overexpression delays endochondral bone formation by inhibiting chondrocyte differentiation.Semantic proximity Read ↗

Cbfa1 is a positive regulatory factor in chondrocyte maturation.Semantic proximity Read ↗

TGF-β/Smad3 Signals Repress Chondrocyte Hypertrophic Differentiation and Are Required for Maintaining Articular CartilageSemantic proximity Read ↗

Atf4 regulates chondrocyte proliferation and differentiation during endochondral ossification by activating <i>Ihh</i> transcriptionSemantic proximity Read ↗

New insight on FGFR3-related chondrodysplasias molecular physiopathology revealed by human chondrocyte gene expression profiling.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.