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Article

Regulation of the transcriptional activation of CTRP3 in chondrocytes by c-Jun.

Molecular and cellular biochemistry - 1 Sept 2012

Kim Mi-Jin, Park Eun-Ju, Lee Wan, Kim Jung-Eun, Park Seung-Yoon

Abstract excerpt

Although C1qTNF-related protein 3 (CTRP3) is highly expressed in cartilage and is involved in the proliferation and migration of chondrocytes, the molecular mechanism governing the transcriptional regulation of CTRP3 in chondrocytes is largely unknown. Here, we demonstrated the mechanism of transcriptional activation of the CTRP3 gene in chondrogenic cells. We observed that c-Jun stimulated CTRP3 promoter...

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PMID: 22644487
DOI: 10.1007/s11010-012-1349-0

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