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Article

Deletion mapping of tumor promotion-susceptibility gene pro1 implicates an RNA polymerase III transcription unit.

Molecular carcinogenesis - 1 Jan 1990

Garrity R R, Hegamyer G A, Seed J L, Colburn N H

Abstract excerpt

The murine gene pro1 has been cloned from JB6 epidermal cell lines that are sensitive to neoplastic transformation by tumor promoters. Insensitive JB6 variants acquire susceptibility to neoplastic transformation by tumor promoters when transfected with pro1. The repetitive nature of pro1 was indicated by sequence and Southern analysis. In contrast, northern analysis of RNA from promotion-sensitive cells revealed...

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PMID: 1698383
DOI: 10.1002/mc.2940030412

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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