Article
Deletion mapping of tumor promotion-susceptibility gene pro1 implicates an RNA polymerase III transcription unit.
Molecular carcinogenesis - 1 Jan 1990
Garrity R R, Hegamyer G A, Seed J L, Colburn N H
Abstract excerpt
The murine gene pro1 has been cloned from JB6 epidermal cell lines that are sensitive to neoplastic transformation by tumor promoters. Insensitive JB6 variants acquire susceptibility to neoplastic transformation by tumor promoters when transfected with pro1. The repetitive nature of pro1 was indi...
Topics
- Alleles
- Animals
- Base Sequence
- Carcinogens
- Cell Line
- Chromosome Deletion
- Chromosome Mapping
- Mice
- Mice, Inbred BALB C
- Molecular Sequence Data
- Proto-Oncogenes
- RNA
- RNA Polymerase III
- Restriction Mapping
- Ribonucleases
- Sensitivity and Specificity
- Transcription, Genetic