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Article

A Novel c-Myc- responsive Gene, JPO1, Participates in Neoplastic Transformation

1 Dec 2001

Abstract excerpt

We have identified a novel c-Myc-responsive gene, named JPO1, by representational difference analysis. JPO1 responds to two inducible c-Myc systems and behaves as a direct c-Myc target gene. JPO1 mRNA expression is readily detectable in the thymus, small intestine, and colon, whereas expression is relatively low in spleen, bone marrow, and peripheral leukocytes. We cloned a full-length JPO1 cDNA that encodes a...

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PMID: 11598121
DOI: 10.1074/jbc.m107357200

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