Article
Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells.
Oncogene - 2 Jul 1998
Cmarik J L, Li Y, Ogram S A, Min H, Reeves R, Colburn N H
Abstract excerpt
Elevated levels of high mobility group (HMG) nonhistone chromosomal proteins I and Y, alternatively spliced members of the HMG-I(Y) family of architectural transcription factors, have been linked with human cancer and with neo-plastic and metastatic phenotypes in model systems. To investigate whether HMG-I(Y) proteins may influence susceptibility to neoplastic transformation, HMG-I(Y) mRNA and protein levels were...
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