Article
Tumor promoter induces high mobility group HMG-Y protein expression in transformation-sensitive but not -resistant cells.
Oncogene - 2 Jul 1998
Cmarik J L, Li Y, Ogram S A, Min H, Reeves R, Colburn N H
Abstract excerpt
Elevated levels of high mobility group (HMG) nonhistone chromosomal proteins I and Y, alternatively spliced members of the HMG-I(Y) family of architectural transcription factors, have been linked with human cancer and with neo-plastic and metastatic phenotypes in model systems. To investigate whe...
Topics
- Alternative Splicing
- Animals
- Carcinogens
- Cell Transformation, Neoplastic
- Gene Expression Regulation, Neoplastic
- Genetic Variation
- HMGA1a Protein
- High Mobility Group Proteins
- Mice
- Polymerase Chain Reaction
- RNA, Messenger
- RNA, Neoplasm
- Skin Neoplasms
- Tetradecanoylphorbol Acetate
- Transcription Factors
- Transcription, Genetic