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Article

CIB1 Is Essential for Mouse Spermatogenesis

1 Nov 2006

Abstract excerpt

CIB1 is a 22-kDa calcium binding, regulatory protein with approximately 50% homology to calmodulin and calcineurin B. CIB1 is widely expressed and binds to a number of effectors, such as integrin alphaIIb, PAK1, and polo-like kinases, in different tissues. However, the in vivo functions of CIB1 are not well understood. To elucidate the function of CIB1 in whole animals, we used homologous recombination in...

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PMID: 16982698
DOI: 10.1128/mcb.01488-06

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