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Essential Roles of the Chromatin Remodeling Factor Brg1 in Spermatogenesis in Mice1

12 Apr 2012

Abstract excerpt

Mammalian spermatogenesis is a complex process that involves spatiotemporal regulation of gene expression and meiotic recombination, both of which require the modulation of chromatin structure. Proteins important for chromatin regulation during spermatogenesis remain poorly understood. Here we addressed the role of BRG1, the catalytic subunit of the mammalian Swi/Snf-like BAF chromatin-remodeling complex, during...

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PMID: 22495890
DOI: 10.1095/biolreprod.111.097097

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