Article
The structure of Apo-wild-type cellular retinoic acid binding protein II at 1.4 A and its relationship to ligand binding and nuclear translocation.
Journal of molecular biology - 27 Oct 2006
Vaezeslami Soheila, Mathes Erika, Vasileiou Chrysoula, Borhan Babak, Geiger James H
Abstract excerpt
CRABPII is a small, cytosolic protein that solubilizes and transfers retinoic acid (RA) to the nucleus while also enhancing its transcriptional activity. We have determined the first high-resolution structure of apo-wild type (WT) CRABPII at 1.35 A. Using three different data sets collected on ap...
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