Article
Crystal structure of rat carnitine palmitoyltransferase II (CPT-II).
Biochemical and biophysical research communications - 4 Aug 2006
Hsiao Yu-Shan, Jogl Gerwald, Esser Victoria, Tong Liang
Abstract excerpt
Carnitine palmitoyltransferase II (CPT-II) has a crucial role in the beta-oxidation of long-chain fatty acids in mitochondria. We report here the crystal structure of rat CPT-II at 1.9A resolution. The overall structure shares strong similarity to those of short- and medium-chain carnitine acyltransferases, although detailed structural differences in the active site region have a significant impact on the...
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