Molecular cloning of two human cellular retinoic acid-binding proteins (CRABP). Retinoic acid-induced expression of CRABP-II but not CRABP-I in adult human skin in vivo and in skin fibroblasts in vitro.

Abstract excerpt

Cellular retinoic acid binding proteins (CRABP) are low molecular weight proteins whose precise function remains unknown. To investigate the role of CRABP in human skin we have cloned the human CRABP-II cDNA as well as the coding region of human CRABP-I. The predicted amino acid sequences of human CRABP-I and CRABP-II demonstrated a 99.3 and 93.5% identity to mouse CRABP-I and CRABP-II, respectively. CRABP-I...

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