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Article

The role of the divergent amino and carboxyl domains on the inactivation properties of potassium channels derived from the Shaker gene of Drosophila.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Sept 1990

Iverson L E, Rudy B

Abstract excerpt

Several products generated from the Drosophila Shaker gene by alternative splicing predict a group of similar proteins with an identical central and variable amino and carboxyl domains. We have constructed 9 Sh cDNAs combining 3 different 5' domains with 3 different 3' domains. RNA transcribed from 6 of these cDNAs induce K+ currents in Xenopus oocytes. All currents share similar properties of voltage dependence,...

Topics

Animals
Cell Membrane
Charybdotoxin
DNA
DNA Restriction Enzymes
Drosophila melanogaster
Electric Conductivity
Gene Expression
Kinetics
Mutation
Oocytes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Potassium Channels

RNA

Scorpion Venoms

Transcription, Genetic

Xenopus

Source

Open in PubMed Open full text

Identifiers

PMID: 1697898
PMCID: PMC6570240

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1697898-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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The role of the divergent amino and carboxyl domains on the inactivation properties of potassium channels derived from the Shaker gene of Drosophila.PMID 1697898Read ↗

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