Article
Alteration of potassium channel gating: molecular analysis of the Drosophila Sh5 mutation.
Neuron - 1 Jul 1990
Gautam M, Tanouye M A
Abstract excerpt
The Drosophila Shaker (Sh) gene encodes a family of voltage-gated K+ channels. Mutant alleles of Sh alter the currents expressed from these channels in a variety of ways. To identify the molecular basis of these alterations, Sh transcript sequences were amplified using the polymerase chain reaction after reverse transcription of mutant RNA. Amplified products from each mutant were cloned and sequenced. Two...
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