Article
A temperature-sensitive splicing mutation in the bimG gene of Aspergillus produces an N-terminal fragment which interferes with type 1 protein phosphatase function.
The EMBO journal - 2 Sept 1996
Hughes M, Arundhati A, Lunness P, Shaw P J, Doonan J H
Abstract excerpt
Progression through anaphase requires high levels of type 1 protein phosphatase (PP1) activity in a variety of eukaryotes, including Aspergillus nidulans. A conditional lethal, temperature-sensitive mutant in one of the Aspergillus PP1 genes, bimG, prevents the normal completion of anaphase when...
Topics
- Alleles
- Amino Acid Sequence
- Aspergillus
- Base Sequence
- Genes, Fungal
- Genes, Lethal
- Molecular Sequence Data
- Mutation
- Peptides
- Phenotype
- Phosphoprotein Phosphatases
- RNA Splicing