Article
A temperature-sensitive splicing mutation in the bimG gene of Aspergillus produces an N-terminal fragment which interferes with type 1 protein phosphatase function.
The EMBO journal - 2 Sept 1996
Hughes M, Arundhati A, Lunness P, Shaw P J, Doonan J H
Abstract excerpt
Progression through anaphase requires high levels of type 1 protein phosphatase (PP1) activity in a variety of eukaryotes, including Aspergillus nidulans. A conditional lethal, temperature-sensitive mutant in one of the Aspergillus PP1 genes, bimG, prevents the normal completion of anaphase when cells are grown at restrictive temperature and this has been shown to be due to a reduction in type 1 phosphatase...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.