The stability of the heme-globin linkage in some normal, mutant, and chemically modified hemoglobins.

Article

The stability of the heme-globin linkage in some normal, mutant, and chemically modified hemoglobins.

The Journal of biological chemistry - 5 Sept 1990

Benesch R E, Kwong S

Abstract excerpt

The rates and equilibria of heme exchange between methemoglobin and serum albumin were measured using a simple new spectrophotometric method. It is based on the large difference between the spectrum of methemoglobin and that of methemealbumin at pH 8-9. The rate of heme exchange was found to be i...

Topics

Female
Fetal Blood
Fetal Hemoglobin
Globins
Heme
Hemoglobin A
Hemoglobin, Sickle
Hemoglobins
Hemoglobins, Abnormal
Humans
Kinetics
Mutation
Pregnancy
Protein Binding

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