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Article

Hairy/Enhancer-of-Split MEGANE and Proneural MASH1 Factors Cooperate Synergistically in Midbrain GABAergic Neurogenesis.

PloS one - 1 Jan 2015

Wende Clara-Zoe, Zoubaa Saida, Blak Alexandra, Echevarria Diego, Martinez Salvador, Guillemot François, Wurst Wolfgang, Guimera Jordi

Abstract excerpt

GABAergic neurons are the primary inhibitory cell type in the mature brain and their dysfunction is associated with important neurological conditions like schizophrenia and anxiety. We aimed to discover the underlying mechanisms for dorsal/ventral midbrain GABAergic neurogenesis. Previous work by us and others has provided crucial insights into the key function of Mgn and Mash1 genes in determining GABAergic...

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Identifiers

PMID: 25993409
DOI: 10.1371/journal.pone.0127681
PMCID: PMC4439124

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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