Article
Effect of phorbol myristate acetate on T cell colony formation, interleukin-2 (IL-2) receptor expression and IL-2 production by cells from patients at all stages of HIV infection.
Clinical and experimental immunology - 1 Aug 1990
Allouche M, Lunardi-Iskandar Y, Varela-Millot C, Itzhaki M, Cornuet P, Meyer P, Jasmin C, Georgoulias V
Abstract excerpt
We and others have shown that several T cell responses induced by the mitogen phytohaemagglutinin (PHA), including T cell colony formation, IL-2 receptor (IL-2R) expression, and IL-2 production are impaired in patients with AIDS and lymphadenopathy syndrome (LAS). We investigated whether phorbol...
Topics
- Antigens, CD
- Antigens, Surface
- Cell Division
- Cells, Cultured
- Drug Synergism
- HIV Infections
- Humans
- Interleukin-2
- Lymphocyte Activation
- Male
- Phenotype