Article
The effect of cytokines on cultured mononuclear cells from patients with B cell chronic lymphocytic leukemia.
Hematological oncology - 1 Jan 2000
Burke F, Griffin D, Elwood N, Davis C, Stamp G, Rohatiner A, Lister T A, Balkwill F
Abstract excerpt
In the past 5 years a number of cytokines have been identified that control B cell development, proliferation, and maturation. The role of such cytokines in the evolution, pathophysiology, and treatment of B cell malignancies is an area of great interest. The in vitro response of freshly isolated...
Topics
- Antigens, Neoplasm
- Antigens, Surface
- Blotting, Northern
- Cell Count
- Cell Survival
- Cytokines
- DNA, Neoplasm
- Humans
- In Situ Hybridization
- Interleukin-6
- Leukemia, Lymphocytic, Chronic, B-Cell
- Leukocytes, Mononuclear
- Phenotype
- RNA, Neoplasm
- Thymidine
- Tumor Cells, Cultured
- Tumor Necrosis Factor-alpha