Article
Effects of phorbol esters and cytokines (interleukin-2,-4, and -6) on the proliferation and surface phenotype of Epstein-Barr virus immortalised human B lymphocytes.
Leukemia & lymphoma - 1 Sept 1992
Kosmas C, Epenetos A A, Courtenay-Luck N S
Abstract excerpt
Epstein-Barr virus (EBV)-induced in vitro infection of peripheral blood mononuclear cells (PBMCs) leads to a polyclonal proliferation and immortalisation of B lymphocytes. In the present study we determined the effects of three different cytokines, interleukin-2 (IL-2), interleukin-4 (IL-4) and i...
Topics
- Antigens, CD
- B-Lymphocytes
- Cell Transformation, Viral
- Herpesvirus 4, Human
- Humans
- Interleukin-2
- Interleukin-4
- Interleukin-6
- Lymphocyte Activation
- Phenotype
- Receptors, Interleukin-2
- Recombinant Proteins
- Tetradecanoylphorbol Acetate