Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Serotonin transporter genotype and acute subjective response to amphetamine.

The American journal on addictions - 1 Jan 2000

Lott David C, Kim Soo-Jeong, Cook Edwin H, de Wit Harriet

Abstract excerpt

The authors have previously shown an effect of dopamine transporter genotype on acute subjective responses to d-amphetamine, which may affect risk of addiction. They now report the results of an evaluation of the role of the serotonin transporter gene (HTT) using a double-blind, placebo-controlled, crossover design in which subjects (N = 101) completed self-report measures of subjective effect. The separate and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Affect
Share to Amphetamine-Related Disorders
Share to Arousal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cross-Over Studies

Share to Double-Blind Method

Share to Minisatellite Repeats

Share to Serotonin Plasma Membrane Transport Proteins

Share to Substance-Related Disorders

Source

Identifiers

PMID: 16966188
DOI: 10.1080/10550490600859868

Genes

HTT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Serotonin transporter genotype and acute subjective response to amphetamine.PMID 16966188Read ↗

Norepinephrine transporter gene variation modulates acute response to D-amphetamine.Semantic proximity Read ↗

Dopamine transporter gene associated with diminished subjective response to amphetamine.Semantic proximity Read ↗

Further evidence of association between amphetamine response and SLC6A2 gene variants.Semantic proximity Read ↗

Polymorphisms in dopamine transporter (SLC6A3) are associated with stimulant effects of D-amphetamine: an exploratory pharmacogenetic study using healthy volunteers.Semantic proximity Read ↗

OPRM1 gene variants modulate amphetamine-induced euphoria in humans.Semantic proximity Read ↗

Does COMT genotype influence the effects of d-amphetamine on executive functioning?Semantic proximity Read ↗

Interactive effects of OPRM1 and DAT1 genetic variation on subjective responses to alcohol.Semantic proximity Read ↗

Monoamine oxidase a and catechol-o-methyltransferase functional polymorphisms and the placebo response in major depressive disorder.Semantic proximity Read ↗

Interindividual variation in anxiety response to amphetamine: possible role for adenosine A2A receptor gene variants.Semantic proximity Read ↗

Candidate gene studies of a promising intermediate phenotype: failure to replicate.Semantic proximity Read ↗

More aroused, less fatigued: fatty acid amide hydrolase gene polymorphisms influence acute response to amphetamine.Semantic proximity Read ↗

Genetic moderation of cocaine subjective effects by variation in the TPH1, TPH2, and SLC6A4 serotonin genes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.