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[Mutational detection of full-length mixed lineage leukemia gene in patients with de novo AML-M4 and M5].

Zhongguo shi yan xue ye xue za zhi - 1 Feb 2012

Wang Qin-Rong, Shi Jing-Yi, Shi Lin, Chen Sai-Juan

Abstract excerpt

Abnormalities of chromosome 11 involving mixed lineage leukemia (MLL) on 11q23 are often seen in acute myeloid leukemia (AML)-M5 or AML-M4. The fusion gene of MLL-PTD and MLL plays a critical role in the pathogenesis of these AML. However, rare chromosome abnormalities have been identified in this type of leukemia. To explore whether there were other MLL gene mutations at M4 and M5, in this study all of the MLL...

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Share to Alternative Splicing
Share to Base Sequence
Share to Chromosomes, Human, Pair 11

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mutational Analysis

Share to Histone-Lysine N-Methyltransferase

Share to Leukemia, Monocytic, Acute

Share to Myeloid-Lymphoid Leukemia Protein

Share to Oncogene Proteins, Fusion

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PMID: 22391156

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SET

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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