Article
In focus: MLL-rearranged leukemia.
Leukemia - 1 Jun 2013
de Boer J, Walf-Vorderwülbecke V, Williams O
Abstract excerpt
The molecular mechanisms underlying oncogenesis in leukemias associated with rearrangement of the Mixed Lineage Leukemia (MLL) gene have received a considerable amount of attention over the last two decades. In this review we will focus on recent studies, published over the past year, that reveal new insights into the multi-protein complexes formed by MLL and MLL fusion proteins, the role of epigenetic...
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