Article
Phenotypic abnormalities in CD8+ T lymphocyte subsets in patients with rheumatoid arthritis.
The Journal of rheumatology - 1 Nov 1991
Sohen S, Romain P L, Rothstein D M, Yamane T, Tanaka S, Anderson P, Schlossman S F, Morimoto C
Abstract excerpt
We analyzed the cell surface phenotype of CD8+ cells in both peripheral blood and synovial fluid (SF) of patients with rheumatoid arthritis (RA) and osteoarthritis (OA). Utilizing the monoclonal antibodies anti-CD45RA, anti-CD29 and anti-S6F1-, one can define both suppressor effector (CD45RA+CD29-S6F1-) and killer effector (CD45RA-CD29+S6F1+) cells within the CD8 population. In patients with OA, normal...
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