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Article

Allele frequency matching between SNPs reveals an excess of linkage disequilibrium in genic regions of the human genome.

PLoS genetics - 8 Sept 2006

Eberle Michael A, Rieder Mark J, Kruglyak Leonid, Nickerson Deborah A

Abstract excerpt

Significant interest has emerged in mapping genetic susceptibility for complex traits through whole-genome association studies. These studies rely on the extent of association, i.e., linkage disequilibrium (LD), between single nucleotide polymorphisms (SNPs) across the human genome. LD describes the nonrandom association between SNP pairs and can be used as a metric when designing maximally informative panels of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16965180
DOI: 10.1371/journal.pgen.0020142
PMCID: PMC1560400

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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