Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Patterns of linkage disequilibrium in the human genome.

Nature reviews. Genetics - 1 Apr 2002

Ardlie Kristin G, Kruglyak Leonid, Seielstad Mark

Abstract excerpt

Particular alleles at neighbouring loci tend to be co-inherited. For tightly linked loci, this might lead to associations between alleles in the population a property known as linkage disequilibrium (LD). LD has recently become the focus of intense study in the hope that it might facilitate the mapping of complex disease loci through whole-genome association studies. This approach depends crucially on the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Genome, Human
Share to Haplotypes
Share to Chromosome Mapping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Demography

Share to Drosophila

Share to Genetics, Population

Share to Linkage Disequilibrium

Share to Pattern Recognition, Automated

Source

Identifiers

PMID: 11967554
DOI: 10.1038/nrg777

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Patterns of linkage disequilibrium in the human genome.PMID 11967554Read ↗

Linkage disequilibrium in the human genome.Semantic proximity Read ↗

Linkage disequilibrium and association mapping: an introduction.Semantic proximity Read ↗

Population genomics: linkage disequilibrium holds the key.Semantic proximity Read ↗

Shaking the tree: mapping complex disease genes with linkage disequilibrium.Semantic proximity Read ↗

Complex phenotypes and phenomenon of genome-wide inter-chromosomal linkage disequilibrium in the human genome.Semantic proximity Read ↗

Linkage disequilibrium patterns of the human genome across populations.Semantic proximity Read ↗

[Linkage disequilibrium in the human genome and its exploitation].Semantic proximity Read ↗

Structure of linkage disequilibrium in humans: genome factors and population stratification.Semantic proximity Read ↗

Lower-than-expected linkage disequilibrium between tightly linked markers in humans suggests a role for gene conversion.Semantic proximity Read ↗

Sequence features in regions of weak and strong linkage disequilibrium.Semantic proximity Read ↗

Linkage disequilibrium between STRPs and SNPs across the human genome.Semantic proximity Read ↗

Randomly distributed crossovers may generate block-like patterns of linkage disequilibrium: an act of genetic drift.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.