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Article

Detecting coevolution through allelic association between physically unlinked loci.

American journal of human genetics - 14 May 2010

Rohlfs Rori V, Swanson Willie J, Weir Bruce S

Abstract excerpt

Coevolving interacting genes undergo complementary mutations to maintain their interaction. Distinct combinations of alleles in coevolving genes interact differently, conferring varying degrees of fitness. If this fitness differential is adequately large, the resulting selection for allele matching could maintain allelic association, even between physically unlinked loci. Allelic association is often observed in...

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Identifiers

PMID: 20381007
DOI: 10.1016/j.ajhg.2010.03.001
PMCID: PMC2869012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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