Article

Classic genome-wide association methods are unlikely to identify causal variants in strongly clonal microbial populations

2021-07-01

Abstract excerpt

Since the advent of genome-wide association studies (GWAS) in human genomes, an increasing sophistication of methods has been developed for more robust association detection. Currently, the backbone of human GWAS approaches is allele-counting-based methods where the signal of association is derived from alleles that are identical-by-state. Borrowing this approach from human GWAS, allele-counting-based methods have...

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Literature Corpus work: b7a6f404-8cf9-58f8-a1b9-f618d019e158
DOI: 10.1101/2021.06.30.450606

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