Article
In vitro and in vivo complementation of the Helicobacter pylori arginase mutant using an intergenic chromosomal site.
Helicobacter - 1 Oct 2006
Langford Melanie L, Zabaleta Jovanny, Ochoa Augusto C, Testerman Traci L, McGee David J
Abstract excerpt
BACKGROUND: Gene complementation strategies are important in validating the roles of genes in specific phenotypes. Complementation systems in Helicobacter pylori include shuttle vectors, which transform H. pylori at relatively low frequencies, and chromosomally based approaches. Chromosomal complementation strategies are susceptible to polar effects and disruption of other H. pylori genes, leading to unwanted...
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