Article
Mosaic DNA imports with interspersions of recipient sequence after natural transformation of Helicobacter pylori.
PloS one - 1 Jan 2008
Kulick Stefan, Moccia Claudia, Didelot Xavier, Falush Daniel, Kraft Christian, Suerbaum Sebastian
Abstract excerpt
Helicobacter pylori colonizes the gastric mucosa of half of the human population, causing gastritis, ulcers, and cancer. H. pylori is naturally competent for transformation by exogenous DNA, and recombination during mixed infections of one stomach with multiple H. pylori strains generates extensive allelic diversity. We developed an in vitro transformation protocol to study genomic imports after natural...
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