Article
Generation of Isogenic Mutant Strains of Helicobacter pylori.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021
Servetas Stephanie L, Whitmire Jeannette M, Merrell D Scott
Abstract excerpt
One important tool in the study of gene function is the construction of mutant strains. Specifically, the construction of isogenic mutant strains imparts researchers with the ability to compare a wild-type strain to a strain that is genetically identical with the exception of the gene of interest. For a bacterial species such as Helicobacter pylori , which is notorious for the genetic heterogeneity seen across...
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