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Article

Negative control of the helix-loop-helix family of myogenic regulators in the NFB mutant.

Cell - 10 Aug 1990

Peterson C A, Gordon H, Hall Z W, Paterson B M, Blau H M

Abstract excerpt

We have characterized a nondifferentiating mouse muscle cell line, NFB, that represses the activity of the helix-loop-helix (HLH) family of myogenic regulators, yet expresses sarcomeric actins. The NFB MyoD gene is silent, but can be activated upon transfection of a long terminal region-controlled chicken MyoD cDNA, resulting in myogenesis. When NFB cells are fused with H9c2 rat muscle cells in heterokaryons, the...

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PMID: 1696180
DOI: 10.1016/0092-8674(90)90014-6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Negative control of the helix-loop-helix family of myogenic regulators in the NFB mutant.PMID 1696180Read ↗

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