Article
Defective myogenesis in NFB-s mutant associated with a saturable suppression of MYF5 activity.
Somatic cell and molecular genetics - 1 Sept 1996
Rohrer D K, Blau H M
Abstract excerpt
Myogenic cell lines have proved to be useful tools for investigating the molecular mechanisms that control cellular differentiation. NFB-s is a mutant myogenic cell line which fails to differentiate in vitro, and can repress differentiation in normal myogenic cells when fused to form heterokaryon...
Topics
- Animals
- Binding Sites
- Cell Differentiation
- Cell Line
- DNA-Binding Proteins
- Genes, Reporter
- Mice
- Mice, Mutant Strains
- Muscle Development
- Muscle Proteins
- Muscle, Skeletal
- Myogenic Regulatory Factor 5
- Myosin Light Chains
- Phenotype
- RNA, Messenger
- Trans-Activators
- Transcription Factors
