Article
Defective myogenesis in NFB-s mutant associated with a saturable suppression of MYF5 activity.
Somatic cell and molecular genetics - 1 Sept 1996
Rohrer D K, Blau H M
Abstract excerpt
Myogenic cell lines have proved to be useful tools for investigating the molecular mechanisms that control cellular differentiation. NFB-s is a mutant myogenic cell line which fails to differentiate in vitro, and can repress differentiation in normal myogenic cells when fused to form heterokaryons. The NFB-s cell line was used here to study the molecular mechanisms underlying such myogenic repression. Using...
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