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Article

Genetic influences on the retention of inorganic mercury.

Archives of environmental & occupational health - 1 Jan 2000

Custodio Hipolito M, Harari Raul, Gerhardsson Lars, Skerfving Staffan, Broberg Karin

Abstract excerpt

Mercury is eliminated as glutathione (GSH) conjugates. GSH production is mediated by glutamyl-cysteine ligase (GCL), and conjugation by glutathione S-transferases (GST). This study tested if polymorphisms in GCL and GST genes modify mercury retention in humans exposed to elemental mercury vapor. Total mercury concentrations in whole blood, plasma and urine, and genotypes for GCLC, GCLM, GSTA1, GSTM1, GSTP1, and...

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Source

Identifiers

PMID: 16961004
DOI: 10.3200/AEOH.60.1.17-23

Genes

GCLM
GCLC
GSTA1
GSTM1
GSTP1
GSTT1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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