Article
Influence of genetic polymorphisms of Hg metabolism and DNA repair on the frequencies of micronuclei, nucleoplasmic bridges, and nuclear buds in communities living in gold mining areas.
Mutation research. Genetic toxicology and environmental mutagenesis - 1 Jul 2024
Espitia-Pérez Lyda, Brango Hugo, Peñata-Taborda Ana, Galeano-Páez Claudia, Jaramillo-García Manolo, Espitia-Pérez Pedro, Pastor-Sierra Karina, Bru-Cordero Osnamir, Hoyos-Giraldo Luz Stella, Reyes-Carvajal Ingrid, Saavedra-Trujillo Diana, Ricardo-Caldera Dina, Coneo-Pretelt Andrés
Abstract excerpt
Fishing communities living near gold mining areas are at increased risk of mercury (Hg) exposure via bioaccumulation of methylmercury (MeHg) in fish. This exposure has been linked to health effects that may be triggered by genotoxic events. Genetic polymorphisms play a role in the risk associated with Hg exposure. This study evaluated the effect of single nucleotide polymorphisms (SNPs) in metabolic and DNA...
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