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Article

Chronic beryllium disease and glutathione biosynthesis genes.

Journal of occupational and environmental medicine - 1 Jun 2006

Bekris Lynn M, Viernes Hannah-Malia A, Farin Federico M, Maier Lisa A, Kavanagh Terrance J, Takaro Tim K

Abstract excerpt

OBJECTIVE: Because glutathione (GSH) has been reported to be increased in chronic beryllium disease (CBD) and is associated with immune modulation, associations between CBD and gene polymorphisms of the rate-limiting enzyme in GSH synthesis, glutamate cysteine ligase (GCL), were investigated. Glutamate cysteine ligase consists of a catalytic subunit (GCLC) and modifier subunit (GCLM). METHODS: Patients with CBD,...

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Source

Identifiers

PMID: 16766924
DOI: 10.1097/01.jom.0000201845.02369.ba

Genes

GCLC
GCLM
TNR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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